Endocrine Abstracts

The increased appetite associated with hyperthyroidism is assumed to be secondary to an increased metabolic rate. However, the role of thyroid hormones in appetite regulation is poorly understood. We hypothesised that thyroid hormones directly regulate food intake and studied the effects of peripheral and CNS administration of tri-iodothyronine (T3) on food intake in male Wistar rats in vivo.A single subcutaneous (s.c.) injection of 4.5 nmol per ...